如果药物能够选择性地到达治疗的靶组织(target tissue)或靶细胞,对治疗疾病是比较理想的。药物注入体内被组织吸收进入血流后分布于组织间隙,细胞及细胞间液。因为药物除在靶组织蓄积外,也在其他组织内蓄积,故有时也引起一些不理想或不必要的药物效应和毒副作用。特别是由于大多数抗癌药物缺乏对肿瘤组织的特异作用,在应用治疗剂量时常常会产生一些毒性,对机体带 If the drug is able to reach the targeted target tissue or target cells selectively, it is ideal for the treatment of the disease. Drugs injected into the body absorbed by the tissue into the blood flow distribution in the tissue space, cells and intercellular fluid. Because drugs accumulate in the target tissue but also accumulate in other tissues, they sometimes cause some undesirable or unnecessary drug effects and side effects. Especially because most anticancer drugs lack specific effects on tumor tissues, they often produce some toxicity when applied therapeutic doses.