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目的:分析高危因素孕妇羊水细胞染色体产前诊断的应用。方法:对确定具有高危因素的100例来孕妇的临床资料进行回顾性分析。结果:100例孕妇中有97例孕妇羊水培养成功,成功率为97.0%;发现有6例孕妇染色体异常核型,异常检出率为6.0%。结论:临床有必要对具有产前诊断指证的孕妇进行羊水细胞培养和染色体核型分析,现阶段羊水细胞染色体检查安全有效,可对胎儿染色体病进行可靠的诊断。
Objective: To analyze the application of prenatal diagnosis of amniotic fluid cell chromosome in pregnant women with high risk factors. Methods: The clinical data of 100 pregnant women who were identified as risk factors were analyzed retrospectively. Results: In 100 pregnant women, 97 cases of pregnant women were successfully cultured in amniotic fluid with a success rate of 97.0%. Six cases of chromosomal abnormalities were found in pregnant women, with an abnormal detection rate of 6.0%. Conclusion: It is necessary to carry out amniotic fluid cell culture and chromosome karyotype analysis in pregnant women with prenatal diagnosis indications. Chromosome examination of amniotic fluid cells at this stage is safe and effective, which can make a reliable diagnosis of fetal chromosomal diseases.