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用免疫组织化学ABC法观察了14例人胎胸腺中六种T细胞和B细胞表面抗原的表达.结果表明,CD4阳性和CD8阳性的细胞主要见于皮质深层,髓质中较少.CD3阳性细胞多分布在髓质,皮质深层有少量阳性细胞.CDla阳性细胞见于皮质.CD25阳性细胞多分布于髓质.该阳性细胞在胎儿胸腺中的分布反映了T细胞的分化.B细胞表面抗原阳性细胞主要分布在髓质,皮质中很少,在髓质及被膜下亦见少数较大并有突起的阳性细胞.后者可能为B细胞的一种亚型或一种基质细胞.
Immunohistochemical ABC method was used to observe the expression of six T cell and B cell surface antigens in 14 human fetal thymus.The results showed that CD4 positive and CD8 positive cells were mainly found in the deep cortical and medulla.CD3 positive cells Distributed in the medulla, a small amount of cortical deep positive cells.CDla positive cells found in the cortex.CD25-positive cells distributed in the medulla.The distribution of positive cells in the fetal thymus reflects the differentiation of T cells.B-cell surface antigen-positive cells Mainly distributed in the medulla, few in the cortex, in the medulla and the capsule also see a few large and protruding positive cells, the latter may be a B cell subtype or a stromal cell.