新生儿溶血病(HDN)一般是指母婴血型不合引起胎儿或新生儿免疫性溶血。能够引起胎儿血管外溶血,出现贫血、水肿、肝脾肿大,甚至造成胎儿死亡~([5]);新生儿黄疸继续性加重时,可继发核黄疸甚至导致死亡。在国内报道的母婴血型不合的免疫性溶血病中,ABO血型不合者约占85.3%,主要发生在母亲是“O”、胎儿血型为“A”或“B”的孕妇中~([4]),HDN严重危害母婴身体健康,随着大家生活 Neonatal hemolytic disease (HDN) generally refers to maternal and fetal blood group incompatibility caused by fetal or neonatal immune hemolysis. Can cause fetal extravascular hemolysis, anemia, edema, hepatosplenomegaly, and even cause fetal death ~ ([5]); neonatal jaundice continued to aggravate, may lead to kernicterus or even death. In the reported maternal-blood incompatible immune hemolytic disease, ABO blood group about 85.3%, mainly occurs in the mother is “O”, the fetal blood type is “A” or “B” In pregnant women ~ ([4]), HDN seriously endanger the health of mother and baby, as we live