抗菌素在临床上对某些病人会产生副反应、毒性反应及变应性反应,而最常见的有青霉素变应性反应。因此,近年来有关抗菌素过敏患者脱敏感作用的研究受到了很大重视。本文则报导65例抗菌素过敏患者(其中对青霉素过敏者为44例,对四环素类——11例,对链霉素——10例)在预先应用各种脱敏感药物之后进行抗菌素治疗的结果。作者指出,根据疾病性质和应用的抗菌素使用不同的脱敏感药物,可以消除各种副反应,从而保证抗菌素疗法顺利进行。一般在注射青霉素或链霉素时应当采用苯海拉明和钙制剂,局部应用抗菌素时——奴佛卡因和麻黄硷,内服四环素时——奴佛卡因、苯海拉明,吸入气雾剂时——奴佛卡因、苯海拉明、麻黄硷及钙制剂,支气管哮喘与变应性鼻炎时,除此以外,并用可的松。此外,对某些 Antibiotics in clinical patients will have side effects, toxicity and allergic reactions, and the most common penicillin allergic reactions. Therefore, in recent years, the research on the desensitization effect of patients with allergy to anaphylaxis has drawn great attention. This article reports the results of an antibiotic treatment of 65 patients with anaphylaxis with allergy to penicillin (44 for tetracyclines, 11 for tetracyclines, and 10 for streptomycin) after pretreatment with various desensitization agents. The authors note that the use of different desensitizing agents for antibiotics based on the nature of the disease and its use can eliminate side effects and ensure successful antibiotic therapy. Diphenhydramine and calcium preparations should generally be used when injecting penicillin or streptomycin. Topical application of antibiotics - novocaine and ephedrine, oral administration of tetracycline - novocaine, diphenhydramine, inhalation aerosol When the agent - novocaine, diphenhydramine, ephedrine and calcium preparations, bronchial asthma and allergic rhinitis, in addition, and cortisone. Also for some