间充质干细胞基因治疗肿瘤新进展

来源 :国际肿瘤学杂志 | 被引量 : 0次 | 上传用户：huangjl41

【摘要】

：

骨髓间充质干细胞(MSC)是骨髓内除造血干细胞和多功能前祖细胞外另一种成体干细胞,具有很强的自我更新能力、多向分化潜能.该细胞具有明显的趋向肿瘤移动并与肿瘤组织楔合的

【作者】

：

吴平唐瑶云赵素萍

【机构】

：

中南大学湘雅医院耳鼻咽喉头颈外科,长沙,410008

【出处】

：

国际肿瘤学杂志

【发表日期】

：

2008年3期

【关键词】

：

间质干细胞基因疗法遗传载体 Mesenchymal stem cell Gene therapy:Genetic vectors

【基金项目】

：

国家自然科学基金;

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骨髓间充质干细胞(MSC)是骨髓内除造血干细胞和多功能前祖细胞外另一种成体干细胞,具有很强的自我更新能力、多向分化潜能.该细胞具有明显的趋向肿瘤移动并与肿瘤组织楔合的生长特性.虽然骨髓间充质干细胞有向肿瘤干细胞转化的风险,但其作为一种克隆载体可以转导治疗基因在体内获得长期稳定表达,对肿瘤的靶向治疗有着广阔的前景.

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间充质干细胞基因治疗肿瘤新进展

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