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为了进一步探索调控肌腱细胞生长的方法，在肌腱细胞体外培养条件下，采用多种手段阻断类胰岛素生长因子１（ＩＧＦ１）受体系统的不同环节，观察其对肌腱细胞生长的负调节作用。结果发现，ＩＧＦ１受体的抗体（ＩＧＦ１Ｒα）和合成的ＩＧＦ１受体的ｍＲＮＡ的反义寡核苷酸链，对肌腱细胞的增殖有负调节作用。认为，在人工肌腱的构建或防止肌腱粘连的实践中，可以考虑使用上述两种物质。
In order to further explore the method of regulating the growth of tendon cells, in vitro culture conditions of tendon cells, using a variety of means to block different aspects of the insulin-like growth factor-1 (IGF 1) receptor system to observe the growth of tendon cells Negative regulation. The results showed that the antisense oligonucleotide chain of IGF-1 receptor antibody (IGF 1Rα) and synthetic IGF 1 receptor mRNA negatively regulate the proliferation of tendon cells. It is considered that in the practice of constructing artificial tendons or preventing tendon adhesion, the use of both of the above substances may be considered.