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目的分析维持性腹膜透析(PD)患者心血管病(CVD)死亡与钙磷代谢的关系。方法把1999年7月至2007年12月在广州医学院第二附属医院死亡的60例PD患者,按是否因CVD死亡分为CVD死亡组和非CVD死亡组,回顾性分析比较两组的性别、年龄、透析时间、脉压差(PP)、血钙(Ca)、血磷(P)、钙磷乘积、甲状旁腺素(PTH)等指标。结果CVD死亡组28例,占47%,非CVD死亡组32例,占53%;两组的年龄、性别、透析时间和血Ca差异无统计学意义,CVD死亡组的PP、血P、钙磷乘积和PTH显著高于非CVD死亡组。结论血P、钙磷乘积和PTH升高与PD患者的CVD死亡密切相关,是CVD死亡的危险因素。
Objective To analyze the relationship between cardiovascular death (CVD) and calcium and phosphorus metabolism in patients with maintenance peritoneal dialysis (PD). Methods Sixty patients with PD who died in the Second Affiliated Hospital of Guangzhou Medical College from July 1999 to December 2007 were divided into CVD death group and non-CVD death group according to CVD death. The gender of the two groups was retrospectively analyzed , Age, dialysis time, pulse pressure (PP), Ca, P, Ca and P, parathyroid hormone (PTH) and other indicators. Results There were 28 cases in CVD death group (47%) and 32 cases (53%) in non-CVD death group. There were no significant differences in age, sex, dialysis time and blood Ca between the two groups. Phosphorus product and PTH were significantly higher than non-CVD death group. Conclusions Blood P, calcium and phosphorus products and elevated PTH are closely related to CVD death in patients with PD, which is a risk factor for CVD death.