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目的分析脑出血患者和脑梗死患者血浆中脂蛋白(a)、总胆固醇(TC)、甘油三酯(TG)、同型半胱氨酸(Hcy)含量的变化,为脑血管疾病的诊断和干预提供数据参考。方法选取北京市丰台区铁营社区卫生服务中心2014年6月—2016年3月47例脑血管疾病患者作为观察组,选取同期于北京市丰台区铁营社区卫生服务中心行健康体检的志愿者46例作为对照组,观察组依据疾病类型分为观察组Ⅰ(脑出血患者,例数=24)和观察组Ⅱ(脑梗死患者,例数=23),采用全自动生化分析仪和配套试剂检测所有患者血浆中脂蛋白(a)、总胆固醇、甘油三酯、同型半胱氨酸含量,并对比分析。结果观察组的脂蛋白(a)、总胆固醇、甘油三酯、同型半胱氨酸含量高于对照组,差异显著(P<0.05);观察组Ⅱ的脂蛋白(a)、同型半胱氨酸含量高于观察组I,差异显著(P<0.05)。结论脑血管疾病患者机体脂蛋白(a)、总胆固醇、甘油三酯、同型半胱氨酸含量表现为增高,脂蛋白(a)及同型半胱氨酸含量与脑梗死的发生密切相关。
Objective To analyze the changes of plasma lipoprotein (a), total cholesterol (TC), triglyceride (TG) and homocysteine (Hcy) levels in patients with cerebral hemorrhage and cerebral infarction. To provide a basis for the diagnosis and intervention of cerebrovascular diseases Provide data reference. Methods From July 2014 to March 2016, 47 patients with cerebrovascular disease in Fengtai District of Beijing were selected as the observation group, and the volunteers who took part in the health examination in Tieying Community Health Service Center of Fengtai District of Beijing during the same period were selected. 46 cases were taken as the control group, and the observation group was divided into observation group Ⅰ (patients with ICH, the number of cases = 24) and observation group Ⅱ (patients with cerebral infarction, the number of cases = 23) according to the type of disease. Using automatic biochemical analyzer and matching reagent Plasma lipoprotein (a), total cholesterol, triglyceride and homocysteine in all patients were detected and compared. Results The levels of lipoprotein (a), total cholesterol, triglyceride and homocysteine in the observation group were significantly higher than those in the control group (P <0.05). The levels of lipoprotein (a), homocysteine The acid content was higher than that of observation group I, the difference was significant (P <0.05). Conclusions The contents of lipoprotein (a), total cholesterol, triglyceride and homocysteine in patients with cerebrovascular diseases are increased. The contents of lipoprotein (a) and homocysteine are closely related to the occurrence of cerebral infarction.