西松烷型二萜类化合物是一大类广泛分布于松脂、烟草、陆地动物及海洋生物体中的具有十四元碳环骨架的化合物。其结构新颖复杂,且大多具有显著和广谱的生物活性。近几十年来,有关这类化合物的研究已引起了人们的极大兴趣。因此,开展这类天然产物及其类似物的全合成及构效关系的研究不仅具有重要的学术价值,而且具有潜在的应用前景。 Cedar diterpenoids are a large group of compounds with a fourteen-membered carbon ring skeleton widely distributed in turpentine, tobacco, land animals and marine organisms. Its structure is novel and complex, and most of them have significant and broad-spectrum biological activity. In recent decades, the research on these compounds has attracted great interest. Therefore, the research on the total synthesis and the structure-activity relationship of such natural products and their analogs not only has important academic value, but also has potential application prospects.