Impact of MGMT Promoter Methylation as a Prognostic Marker in Patients with High Grade Glioma: A Sin

来源 :癌症治疗(英文) | 被引量 : 0次 | 上传用户：wjwjwwj

【摘要】

：

Objectives: 1) To correlate the methylation status of the O-6-methylguanine-DNA-methyltransferase (MGMT promoter gene) and response to alkylating agent-based tr

【作者】

：

Vinu Sarathy Srinivasa Belagut

【机构】

：

DepartmentofMedicalOncology

【出处】

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癌症治疗(英文)

【发表日期】

：

2019年10期

【关键词】

：

GLIOBLASTOMA MGMT PROMOTER METHYLATION MGMT Gene Aklylating AGENTS TEMOZOLOMIDE

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Objectives: 1) To correlate the methylation status of the O-6-methylguanine-DNA-methyltransferase (MGMT promoter gene) and response to alkylating agent-based treatment in high-grade gliomas. Background: The MGMT gene is epigenetically silenced by promoter

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Impact of MGMT Promoter Methylation as a Prognostic Marker in Patients with High Grade Glioma: A Sin

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