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应用双抗体放射免疫法测定了51例颅内占位病患者及25例无颅内占位病患者脑脊液等的铁蛋白。发现颅内转移癌病人铁虽白明显高于胶质瘤病人。而胶质瘤病人又高于脑脓肿和颅内血肿病人。提示铁蛋白测定对上述疾病的鉴别诊断有一定意义,并推测颅内恶性肿瘤可能有过度合成和释放铁蛋白的能力。
Twenty - one patients with intracranial space occupying disease and 25 patients with cerebrospinal fluid without intracranial space occupying disease were assayed by double antibody radioimmunoassay. Iron intracranial metastases were found in patients with iron significantly higher than glioma patients. The glioma patients and brain abscess and intracranial hematoma patients. Prompt determination of ferritin on the differential diagnosis of the disease has some significance, and speculated that intracranial malignant tumors may over-synthesis and the ability to release ferritin.