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目的分析北京市朝阳区HIV抗体筛查阳性标本的确证符合情况,了解不同抗体筛查实验室检测状况以及不同人群确证阳性状况,为指导检测工作提供依据。方法对2011年-2015年送检的4 663件筛查阳性标本采用蛋白免疫印迹法(Western Blot,WB)进行确证实验,并对检测结果的确证符合率进行分析。结果 4 663件样本确证阳性率为77.57%,来自监管系统和疾控系统的确证阳性率较高,为94.57%和89.09%;社区卫生服务中心的确证阳性率最低,为54.11%;15岁~和30岁~年龄组确证符合率最高,分别为83.36%和81.38%;检测方法中确证阳性率最高的为ELISA方法。结论日常工作中应注意病人的流行病学资料与确证结果结合分析,同时,建议在日常工作中对于可疑样本应在有条件的情况下,进行核酸检测,避免漏检和误检。
Objective To analyze the confirmations of HIV antibody screening positive samples in Chaoyang District, Beijing, to understand the detection status of different antibody screening laboratories and to confirm the positive status in different populations so as to provide the basis for the detection and detection. Methods A total of 4 663 positive specimens were screened by Western Blot (WB) from 2011 to 2015, and the confirmatory test results were analyzed. Results The positive rate of confirmed samples from 4 663 samples was 77.57%. The confirmed positive rates from regulatory system and disease control system were 94.57% and 89.09%, respectively. The confirmed positive rate of community health service center was the lowest, 54.11% And the age group of 30 ~ age confirmed the highest rate of coincidence, respectively 83.36% and 81.38%; detection method confirmed the highest positive rate for the ELISA method. Conclusions The daily work should pay attention to the patient’s epidemiological data combined with the results of confirmatory test. At the same time, it is suggested that in the daily work, the suspicious samples should be tested under the condition, to avoid missing and false positives.