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本文比较了冠心病病人(CHD)、非胰岛素依赖型糖尿病病人(NIDD)、NIDD合并CHD病人及正常对照组的血脂、Apo AI、A Ⅱ水平。Logistic回归分析表明,主要是TC的升高与Apo AI水平的降低对冠心病的发生有较密切的关系。与正常对照相比,LDL-C/Apo AI可较其它脂代谢指标更敏感地反映NIDD患者的脂代谢紊乱。无论是血脂,ApoAI、AII还是HbA_2都不能作为区别NIDD与NIDD合并CHD患者的指标。Apo AI、AII与HbA_1、糖尿病病程之间无相关。
This article compares the levels of serum lipids, Apo AI and A Ⅱ in patients with coronary heart disease (CHD), non-insulin dependent diabetes mellitus (NIDD), NIDD patients with CHD and normal controls. Logistic regression analysis showed that the main reason is that the increase of TC and the decrease of Apo AI level have a close relationship with the occurrence of coronary heart disease. Compared with normal controls, LDL-C / Apo AI can reflect lipid disorders in NIDD patients more sensitively than other lipid metabolism parameters. Neither blood lipids nor ApoAI nor AII nor HbA 2 can be used as a marker to distinguish patients with NIDD and NIDD complicated by CHD. Apo AI, AII and HbA_1, no correlation between diabetes duration.