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一、免疫网络与抗独特型抗体免疫网络学说是Jerne在1974年提出的。该学说指出,任何抗体分子或淋巴细胞表面的抗原受体的可变区,都存在着独特型(idiotype,简称Id或Ab_1),该Id可被自身的另一些淋巴细胞识别而诱导产生抗独特型抗体(anti-idiotype antibody,简称anti-Id或Ab_2),而Ab_2又可引起另一抗独特型抗体(简称anti-anti-Id或Ab_3)的产生。如此循环往复,在体内构成了一个复杂的Id、anti-Id网络,并通过反馈机制形成了一系列的链锁反应。而机体的免疫应答
First, the immune network and anti-idiotypic antibody immune network theory is Jerne proposed in 1974. The doctrine states that idiotypes (Id or Ab_1) are present in any variable region of an antibody molecule or antigen receptor on the surface of lymphocytes and are identifiable by other lymphocytes of their own to induce anti-idiotypic Anti-idiotype antibody (anti-Id or Ab_2), Ab 2 can lead to the production of another anti-idiotypic antibody (anti-anti-Id or Ab_3). This cycle of reciprocation, in the body constitutes a complex Id, anti-Id network, and formed a series of chain reaction feedback mechanism. The body’s immune response