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作者等比较了一系列典型的海参皂甙类[刺参甙(Stichoposide)A和C;海参素(Holothurine)A和B;瓜海参甙G(Cucumarioside G)],海星皂甙(Asterosa-ponin)以及植物来源的三萜皂甙-葳严仙皂甙(Caulo-side C)和茶皂甙(Thesaponin)的细胞毒效应。方法是将静置培养在陪替氏培养基中的0.1ml上述皂甙水溶液加至海胆(Strongylocentrotus intermedius)卵(每ml海水于20°含海胆卵2000～3000只)中。根据海胆受精卵发育的形态学评价皂甙的细胞毒活性:(一)没有抑制作用;(+)异常发育并在32～64裂球阶段胚胎死亡;(++)在1裂球阶段分裂停止。结果表明,海参皂
The authors compared a series of typical sea cucumber saponins [Stichoposide A and C; Holothurine A and B; Cucumarioside G], Asterosa-ponin and plants. The cytotoxic effects of Caulo-side C and Thesaponin from the sources of triterpenoid saponins. The method was to add 0.1 ml of the above aqueous solution of saponin, which was statically cultivated in a petri dish, to eggs of Strongylocentrotus intermedius (2000-300 pieces of sea urchin egg per ml of sea water per ml). The cytotoxic activity of saponin was evaluated according to the morphology of the fertilized eggs of sea urchins: (i) no inhibitory effect; (+) abnormal development and embryo death at 32 to 64 fissile stages; (++) fission at 1 fissure stage. The results showed that sea cucumber soap