胃癌动物模型的建立,有利于验证各种可疑的致癌、促癌因素、阐明胃癌的发病机理,同时有利于探讨抗胃癌药物的作用机理。因此探讨建立诱癌期较短、诱癌率较高且发病机理与临床胃癌相类似的胃癌动物模型具有重要意义。研究表明,胃溃疡和饮食中的亚硝基化合物是胃癌发生和发展的重 The establishment of an animal model of gastric cancer is conducive to validating various suspicious carcinogenic and tumor-promoting factors and elucidating the pathogenesis of gastric cancer, and at the same time it is beneficial to explore the mechanism of action of anti-gastric cancer drugs. Therefore, it is of great significance to explore the establishment of an animal model of gastric cancer with a shorter cancer-inducing period, a higher cancer-inducing rate and a similar pathogenesis as clinical gastric cancer. Studies have shown that gastric ulcer and dietary nitroso compounds are the occurrence and development of gastric cancer