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肾动脉狭窄病人置入支架,治疗的效果存在着分歧。《CORAL研究》观察947例严重肾动脉狭窄和收缩性高血压或慢性肾脏病人。比较用支架加标准内科治疗与单用内科治疗。后者包括一种血管紧张素受体阻滞剂,合用或不合用一种利尿剂,一种钙通道阻滞剂和一种他汀。随访5年。复合第一终点为因肾或心血管病死亡、心肌梗死、脑卒中、充血性心力衰竭住院、进行性肾功能不良或肾移植。结果 2组无大差异。全因死亡2组无差异。单用药物治疗组收缩压降低(15.6±25.8)mmHg,
Patients with renal artery stenosis into the stent, the effect of treatment there are differences. The CORAL study looked at 947 patients with severe renal artery stenosis and contracting hypertension or chronic kidney disease. Compared with standard stent with medical treatment and medical treatment alone. The latter includes an angiotensin receptor blocker, with or without a diuretic, a calcium channel blocker and a statin. Followed up for 5 years. The composite first endpoint was hospitalized for renal or cardiovascular death, myocardial infarction, stroke, congestive heart failure, progressive renal dysfunction or kidney transplantation. Results 2 groups no major differences. All-cause death in two groups no difference. Systolic blood pressure was lower (15.6 ± 25.8) mmHg in the single drug treatment group,