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Objective: The aim of this study was to evaluate the efficacy of three-phase contrast material-enhanced MRI in assessing no-surgical treatment response in peripheral bronchogenic carcinoma preliminarily.Methods: Twenty-two patients with bronchogenic carcinoma after no-surgical treatment underwent three-phase contrast material-enhanced MRI.Three scans were obtained at 25 s, 120 s and 180 s respectively after nonionic contrast material was administrated via the antecubital vein at a rate of 2 roLls by using an autoinjector.Precontrast and postcontrast signal intensity on every scan was recorded.Peak Height (PH) and Maximum Enhancement (Emax) were calculated.Enhancement patte was evaluated on the images obtained at 120 s and 180 s after injection of contrast medium.Results: Precontrast signal intensity, postcontrast signal intensity at 120 s and 180 s were 478±108, 926±209 and 1050±252.PH (571±225) and Emax (119±49) of bronchogenic carcinoma after no-surgical treatment were significantly lower than those of bronchogenic carcinoma without any therapy (mean PH 655, mean Emax 150) (t=2.178, P=0.005<0.05, t=4.196, P=0.001<0.05).Six cases among 22 appeared homogeneous enhancement at 180 s.At 120 s, there were 4 cases with inhomogeneous enhancement, 1 case with homogeneous enhancement, 1 case with peripheral enhancement among the 6 cases.Conclusion: Bronchogenic carcinoma after no-surgical treatment shows a gradual increase to the PH after administration of contrast material.Three-phase contrast material-enhanced MRI can reflect the blood supply of bronchogenic carcinoma and might be effective approach for evaluation of no-surgical treatment response in bronchogenic carcinoma.