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目的:针对乳腺浸润性导管癌患者,讨论其超声征象与ER、C-erbB-2表达的关系,为日后的临床诊断提供参考与指导。方法:选择我院于2015年5月--2016年3月收治的乳腺浸润性导管癌患者138例为研究对象。观察其超声征象与ER、C-erbB-2表达的关系,包括边缘毛刺征象、微钙化、后方回声衰减3个方面。结果:在超声征象当中,发现患者的ER阳性率为50.7%(70/138),超声显示有边缘毛刺征等患者高于不具备特征患者(P<0.05);患者的C-erbB-2表达率为29.0%(40/138),有微钙化征象者高于无微钙化征象者(P<0.05)。结论:乳腺浸润性导管癌患者,超声征象集中在边缘毛刺征象、后方声衰减征象等,可以此来预测患者的ER水平。利用微钙化征象,可有效分析患者的C-erbB-2表达水平。日后在临床诊断中,可以推广应用。
OBJECTIVE: To investigate the relationship between the ultrasound signs and the expression of ER and C-erbB-2 in patients with invasive ductal carcinoma of the breast, and to provide reference and guidance for clinical diagnosis in future. Methods: 138 cases of invasive ductal carcinoma of the breast in our hospital from May 2015 to March 2016 were selected as the research object. Observe the relationship between the ultrasound signs and the expression of ER and C-erbB-2, including three aspects: edge burr sign, microcalcification and posterior echo attenuation. Results: Among the ultrasound signs, the positive rate of ER was 50.7% (70/138). Ultrasound showed that the patients with marginal burr were higher than those without the characteristic (P <0.05). The expression of C-erbB-2 The rate was 29.0% (40/138), with signs of micro-calcification was higher than those without signs of micro-calcification (P <0.05). CONCLUSIONS: In patients with invasive ductal carcinoma of the breast, the ultrasonographic features are concentrated on marginal burr signs and posterior acoustic signs of attenuation, which can be used to predict the level of ER in patients. The use of micro-calcification signs, can effectively analyze the patient’s C-erbB-2 expression levels. In the future in clinical diagnosis, can promote the application.