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目的探讨氯吡格雷联合阿托伐他汀钙治疗脑梗死的临床疗效。方法选取2014—2015年任丘市人民医院收治的脑梗死患者66例,采用随机数字表法将其分为对照组与观察组,各33例。对照组患者给予阿托伐他汀钙治疗,观察组患者在对照组基础上加用氯吡格雷治疗。比较两组患者的神经功能缺损评分量表(NIHSS)评分、日常生活能力量表(ADL)评分、生活质量评分、临床疗效、不良反应发生情况。结果观察组总有效率、ADL评分、生活质量评分均高于对照组,差异有统计学意义(P<0.05);NIHSS评分、不良反应发生率均低于对照组,差异有统计学意义(P<0.05)。结论氯吡格雷联合阿托伐他汀钙治疗脑梗死的临床疗效显著,且不良反应少。
Objective To investigate the clinical efficacy of clopidogrel combined with atorvastatin calcium in the treatment of cerebral infarction. Methods Sixty-six patients with cerebral infarction who were admitted to Renqiu People’s Hospital from 2014 to 2015 were divided into control group and observation group with 33 cases in each group by random number table. Patients in the control group were treated with atorvastatin calcium. Patients in the observation group were treated with clopidogrel on the basis of the control group. The NIHSS score, ADL score, quality of life score, clinical efficacy and incidence of adverse reactions were compared between the two groups. Results The total effective rate, ADL score and quality of life scores of the observation group were higher than those of the control group (P <0.05), NIHSS score and adverse reaction rate were lower than the control group (P <0.05). Conclusion Clinical efficacy of clopidogrel combined with atorvastatin calcium in the treatment of cerebral infarction is significant and has few adverse reactions.