论文部分内容阅读
目的观察降纤酶联合低分子量肝素 (LMWH)对急性脑梗死的治疗效果。方法将脑梗死患者随机分成降纤酶联合 LMWH治疗组与降纤酶对照组。对照组应用降纤酶 10 U静脉滴注 ;治疗组在此基础上应用 L MWH 5 0 0 0 U,每 12小时腹部皮下注射 1次 ,连用 5天。治疗前后对神经功能缺损进行评分。结果治疗组显效率 74.3 % ,明显高于对照组 67.9% ,总有效率 96.3 %亦明显高于对照组85 .7% (P<0 .0 5 ) ,进展性脑卒中的发生率治疗组为 1.2 % ,明显低于对照组 8.9% (P<0 .0 1)。结论降纤酶联合 L MWH治疗急性脑梗死能够明显改善临床症状 ,降低致残率 ,并能够预防进展性脑卒中发生
Objective To observe the therapeutic effect of defibrase combined with low molecular weight heparin (LMWH) on acute cerebral infarction. Methods Patients with cerebral infarction were randomly divided into defibrase combined LMWH treatment group and defibrase control group. In the control group, 10μL defibrase was used for intravenous infusion. On the basis of this, the treatment group was given L MWH 50,000 Lo, subcutaneously once every 12 hours for 5 days. Neurological deficits were scored before and after treatment. Results The effective rate of treatment group was significantly higher than that of control group (74.3%), significantly higher than that of control group (67.9%), and the total effective rate was 96.3% (85.7%). The incidence of progressive stroke was 1.2%, significantly lower than the control group 8.9% (P <0. Conclusion Defibrase combined with L MWH in the treatment of acute cerebral infarction can significantly improve the clinical symptoms, reduce the disability rate, and can prevent the occurrence of progressive stroke