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目的：了解郑州市近5年来无偿献血者输血传播感染指标的筛查情况，为制定预防传染病输血传播、减少血液资源浪费措施提供依据。方法对2009-2013年郑州市无偿献血者人群经输血传播感染标志物 HBsAg、抗-HCV、抗-TP、抗-HIV 的检测结果进行统计学分析。结果5年共采集无偿献血标本858772份，HBsAg、抗-HCV、抗-TP、抗-HIV 的总体阳性率分别为0.41%、0.42%、0.31%、0.16%。4项指标阳性率的不同年份间比较和不同性别间比较差异均有统计学意义（P ＜0.05）；HBsAg、抗-HCV 和抗-TP 阳性率不同月份间比较差异均有统计学意义（P ＜0.05），抗-HCV、抗-TP 和抗-HIV 阳性率不同年龄组间比较差异均有统计学意义（P ＜0.05）。抗-HIV 确诊阳性检出率为0.10‰。结论加强无偿献血知识的宣传和经输血传播感染标志物的检测，是在保证临床用血安全情况下提高血液资源利用率的重要措施。“,”Objective To understand the blood screening situation of Zhengzhou voluntary blood donors in recent 5 years, and to provide the basis for taking measures to prevent transfusion-transmitted diseases and reduce the waste of blood resources. Methods Screening results of the blood four infectious indicators including HBsAg,anti-HCV,anti-TP,anti-HIV in Zhengzhou voluntary blood donors from 2009 to 2013 were collected and analyzed. Results During the 5 years,the positive rates of HB-sAg,anti-HCV,anti-TP,anti-HIV in 858 772 voluntary blood donors were 0. 41% ,0. 42% ,0. 31% and 0. 16% respectively. Each infectious indicator positive rates in different years and different sex had significant differences respectively(all P < 0. 05). The positive rates of HBsAg,anti-HCV and anti-TP had significant differences in different month(P < 0. 05). The positive rates of anti-HCV,anti-TP and anti-HIV had significant differences in different age groups(P < 0. 05). The confirmed positive rate of anti-HIV was 0. 10‰. Conclusion Strengthening the propaganda of voluntary blood knowledge before blood donation and detec-tion of transfusion-transmitted infectious indicators,which is an important measure to improve the blood resource utilization in as-suring the safety transfusion.