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目的：检测急性胰腺炎（ Ａ Ｐ）鼠血清 Ｎ Ｏ浓度并讨论其意义。方法： Ｗｉｓｔａｒ 大鼠５６ 只随机分为实验组（３０ 只）和对照组（２６ 只）。经胰胆管注射牛磺胆酸钠诱发大鼠急性胰腺炎模型。术后６ ｈ、１２ ｈ 测定各组鼠血清 Ｎ Ｏ浓度。结果： Ａ Ｐ鼠血清 Ｎ Ｏ水平明显升高（ Ｐ＜ ０．００１）。结论： Ｎ Ｏ 参与了 Ａ Ｐ的病理生理过程。
Objective: To detect the concentration of serum NO in acute pancreatitis (A P) rats and to discuss its significance. Methods: Fifty-six Wistar rats were randomly divided into experimental group (n = 30) and control group (n = 26). Pancreatic duct injection of sodium taurocholate induced acute pancreatitis in rats model. After 6 h, 12 h, serum N concentration in each group was measured. Results: The serum N O level in A P rats was significantly increased (P <0.001). Conclusion: N O is involved in the pathophysiology of A P.