对12例主动脉粥样硬化不同阶段病变标本进行扫描电镜观察,其中有脂点或脂纹3例,纤维斑块4例,复合病变5例。脂点和脂纹病变呈细条状平行分布或呈圆形和不规则形,部分病变表面呈波浪状或有浅小溃破,小病灶可相互融合。病灶表面的内皮细胞可肺胀或出现虫蛀状损害,或有圆形小泡膨出并进一步形成浅表性圆形缺损;部分内皮脱落,局部有血小板和纤维素粘附。内皮损害可能是由不同因素 Twelve cases of aortic atherosclerosis at different stages of the lesion were observed by scanning electron microscopy, in which there are three fat spots or fat pattern, four cases of fibrous plaque, complex lesions in 5 cases. Fat spots and fat pattern lesions were thin strips parallel or round and irregular shape, some lesions were wavy or slightly ulcerated surface, small lesions can be integrated with each other. Endothelial cells on the surface of the lesion may be swollen or with worm-eaten lesions, or have bulging round bullae and further forming superficial round defects; some of the endothelium may shed and local platelets and cellulose may adhere. Endothelial damage may be caused by different factors