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本文介绍了国产伤寒Vi多糖菌苗在湖北地区对6307名18～55岁健康成人进行了重点和大面积人体反应观察。结果表明：该苗安全性好，无明显副反应。重点观察接种后8、24和48小时三个时间段的全身和局部反应，以弱反应为主，无一例强反应。总体反应率分别为11.l％和2.36％，为伤寒的预防和疫苗的广泛使用展示了良好的前景。
This article describes the domestic typhoid Vi polysaccharide vaccine in Hubei Province on 6307 healthy adults aged 18 to 55 conducted a focused and large-scale human response observed. The results showed that: The seedling safety, no obvious side effects. We focused on the systemic and local reactions at 8, 24 and 48 hours after inoculation, with weak reaction and no strong reaction. The overall response rates were 11.l% and 2.36%, respectively, showing good prospects for typhoid prevention and the widespread use of vaccines.