目的了解手足口病在邳州市的流行病学和病原学特征,为制定手足口病防控策略提供科学依据。方法对邳州市2009—2013年手足口病发病资料采用描述流行病学方法进行统计和分析。结果 2009—2013年全市共报告手足口病病例2 601例,年平均发病率29.29/10万。发病高峰为4—7月,占病例报告总数的71.90%。男女性别比为1.96∶1,发病年龄主要为5岁以下儿童,占病例报告总数的97.81%,其中又以3岁以下婴幼儿发病率为最高。职业以散居儿童为主,占92.50%。5年内引起邳州市手足口病流行的主要病原体为肠道病毒71型,占病原学检测阳性数的79.76%。结论手足口病发病具有明显的性别、年龄和季节性差异,应加强病原学监测和重点人群的防控。 Objective To understand the epidemiological and etiological characteristics of hand-foot-mouth disease in Danzhou and provide a scientific basis for the prevention and control of hand-foot-mouth disease. Methods The epidemiological data of hand-foot-mouth disease in Zhuozhou from 2009 to 2013 were collected for statistical analysis. Results A total of 2 601 HFMD cases were reported in the city from 2009 to 2013, with an average annual incidence of 29.29 / 100 000. The peak incidence was from April to July, accounting for 71.90% of the total number of case reports. The male-to-female sex ratio was 1.96: 1, and the main age of onset was children under 5 years old, accounting for 97.81% of the total number of case reports. Among them, the incidence of infants and young children under 3 was the highest. Occupation of scattered children, accounting for 92.50%. The main pathogen that caused the epidemic of hand, foot and mouth disease in Pizhou in 5 years was enterovirus 71, accounting for 79.76% of the positive number of pathogen detection. Conclusion The incidence of hand, foot and mouth disease has obvious gender, age and seasonal differences. Etiological monitoring should be strengthened and prevention and control of key populations should be strengthened.