1971年,本室应用小鼠L6565白血病小鼠的胸腺悬液,给昆明种小鼠腹腔接种,建立了SRS腹水型瘤株,迄今已传344代。由于能在多种品系小鼠中100％生长,传代方法简便,并已证明瘤细胞内、外含有大量致白血病活性的A型及C型病毒,所以为国内不少单位作为实验研究的模型。为了探讨该瘤株细胞的特性,曾应用不同的方法进行了研究。 In 1971, the thymus suspension of mouse L6565 leukemia mice was used in this laboratory to vaccinate Kunming mice intraperitoneally, and SRS ascites tumor strains were established. So far, 344 generations have passed. Because it can grow 100% in various strains of mice, the passage method is simple, and it has been proved that the tumor cells inside and outside contain a large number of type A and type C viruses that cause leukemia activity. Therefore, many domestic units are used as experimental models. In order to investigate the characteristics of the cells of this tumor strain, different methods have been studied.