马来酸噻吗心安(Timolol maleate)是一种新的对心脏无选择作用的较强β-受体阻滞药(与心得安以毫克为单位进行相比约强6倍),无内源性拟交感活性或膜稳定(“奎尼丁样”)作用。它是一种强的血浆肾素活性抑制剂,当并用噻嗪类利尿药时一般能防止后者诱导肾素活性增加。它的血液动力学性 Timolol maleate is a new, potent β-blocker with no cardiac effect (approximately 6-fold more potent than propranolol), without endogenous Sympathetic activity or membrane stability (“quinidine-like”) effect. It is a potent inhibitor of plasma renin activity that generally prevents the latter from inducing an increase in renin activity when used in combination with thiazide diuretics. It’s hemodynamic