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目的:探讨恶性妊娠性滋养细胞肿瘤(MGTT)患者的子宫动脉血液动力学变化。方法:采用彩色多普勒血流显像(CDBFI)技术测定了正常妇女20例和MGTT30例化疗前、后的子宫动脉血流阻力指数(RI)值。结果:化疗前MGTT组的子宫动脉RI值较正常组低(P<0.01),显示了MGTT子宫血流低阻特性;化疗有效者,经≥3个疗程化疗后子宫动脉RI值较化疗前明显增高(P<0.05)。结论:用CDBFI技术检测子宫动脉血流参数有助于MGTT的诊断及观察化疗疗效。
Objective: To investigate the changes of uterine artery hemodynamics in patients with malignant gestational trophoblastic tumor (MGTT). Methods: The color Doppler flow imaging (CDBFI) technique was used to determine the value of uterine artery resistance index (RI) in 20 normal women and 30 MGTT patients before and after chemotherapy. Results: The RI of uterine artery in MGTT group before chemotherapy was lower than that in normal group (P <0.01), showing the low resistivity characteristic of MGTT uterine blood flow. The effective rate of uterine artery RI Before being significantly higher (P <0.05). Conclusion: The detection of uterine arterial blood flow parameters by CDBFI is helpful for the diagnosis of MGTT and the curative effect of chemotherapy.