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胃癌是我国目前发病率和死亡率最高的恶性肿瘤之一,也是最常见的恶性肿瘤之一,居消化道肿瘤之首,基质金属蛋白酶(matrix metallo-proteinases,MMPs)在胃癌浸润和转移中的作用已成为研究热点。信号传导及转录激活因子3(sig-nal transducers and activator of transcription,STAT3)在胃癌组织中异常表达,并与胃癌的侵袭转移等密切相关,为了进一步了解它们之间的关系,特综述MMPs及STAT3与胃癌的研究进展如下。
Gastric cancer is one of the most morbid and morbid malignant tumors in our country at present, and is also one of the most common malignant tumors. In the first place of gastrointestinal cancer, gastric cancer is the precursor of matrix metallo-proteinases (MMPs) in the invasion and metastasis of gastric cancer Function has become a research hotspot. In order to further understand the relationship between the expression of STAT3 and signal transducers and activators of transcription (STAT3) in gastric cancer tissues, and with the invasion and metastasis of gastric cancer, Research progress with gastric cancer is as follows.