论文部分内容阅读
目的 探讨采用皮质激素联合小剂量放疗治疗眼眶炎性假瘤的有效性。方法 2 7例眼眶炎性假瘤患者 (其中肌炎型 12例 ,弥漫型 7例 ,后部型 3例 ,前部型 5例 ) ,首先采取口服强的松 40~ 60mg/日 ,1~ 2周后逐渐减量 ,2 0~ 3 0天后停药。停药后采用小剂量放射治疗 (钴 -60经眶外侧壁眶尖部照射 ,总量 2 0Gy ,2周内分 10次给予 ,2Gy/次 )。 结果 随访 3年 ,2 7例患者经上述综合治疗后眼痛、眼球突出、眼球运动障碍等症状消失者 2 3例 ,占 85 2 % ;部分减轻者 2例 ,占7 4% ;无效者 2例 ,占 7 4% ;随访 3年 ,2 3例均无复发。结论 皮质激素联合小剂量放射治疗可显著减轻眼眶炎性假瘤患者的临床症状 ,提高治愈率 ,减少复发
Objective To investigate the effectiveness of corticosteroid combined with low-dose radiotherapy in the treatment of orbital inflammatory pseudotumor. Methods Twenty-seven patients with orbital inflammatory pseudotumor, of which 12 were myositis, 7 were diffuse, 3 were posterior and 5 were anterior. Gradually taper after 2 weeks, 20 ~ 30 days after the withdrawal. After discontinuation of small doses of radiation therapy (cobalt-60 orbital foramen lateral orbital irradiation, the total 20Gy, 2 weeks, 10 times given, 2Gy / times). Results The patients were followed up for 3 years. Twenty-seven patients (85%) had eye pain, prominent eyeballs and eye movement disorders disappeared after the above comprehensive treatment. Among them, 2 cases were partly relieved (74%), while 2 were ineffective Cases, accounting for 74%; 3 years follow-up, no recurrence in 23 cases. Conclusions The combination of corticosteroids and low dose radiation therapy can significantly reduce the clinical symptoms of patients with orbital inflammatory pseudotumor, improve the cure rate and reduce recurrence