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颅骨转移瘤临床较少见,我院从1987～1997年5月共收治17例,均经手术或病理证实,结合文献报告如下。 1 临床资料 1.1 一般资料 男7例,女10例。年龄16岁～78岁,平均55岁。病程20天～1年半,平均45个月。肿瘤部位:颅骨盖部13例(76.5％),包括右额1例、左额顶2例、右颞4例、左颞枕1例、右顶1例、后枕4例。颅底部4例(23.5％):包括右眶顶2例、左眶尖1例、左岩骨1例。合并有全身性多发骨转移1例。 1.2 临床表现 颅骨上有包块者10例,多数包块较硬,基底宽,边界不清。伴局部疼痛的8例。眶部病变3例,均有不同程度眼球突出、视力下降、眼痛。肿瘤向内生长3例,均伴有眼底水肿。左侧岩骨1例,伴有左侧面瘫,饮水呛。有1例局部穿刺抽出鲜红色血液。本组病人住院期间均行全身各项检查,有8例未发现原发灶;6例发现为肺癌,肝癌2例,甲状腺癌1例。
Skull metastases clinical less common in our hospital from 1987 to May 1997 were treated in 17 cases were confirmed by surgery or pathology, combined with the literature reported as follows. 1 Clinical data 1.1 General Information 7 males and 10 females. Age 16 years old to 78 years old, average 55 years old. Duration of 20 days to 1 year and a half, an average of 45 months. Tumor site: The cranial lid in 13 cases (76.5%), including the right forehead in 1 case, 2 cases of the left frontal, right temporal in 4 cases, left temporal pillow in 1 case, right in 1 case and posterior pillow in 4 cases. The skull base in 4 cases (23.5%): including right orbital roof in 2 cases, left orbital apex, left petrosal bone in 1 case. One case complicated with multiple multiple bone metastases. 1.2 Clinical manifestations of skull in 10 cases were mass, most of the mass of hard, wide base, the border is not clear. 8 cases with local pain. Orbital lesions in 3 cases, both with varying degrees of prominent eyesight, vision loss, eye pain. Tumor growth in 3 cases, are associated with fundus edema. A case of the left side of the rock bone, accompanied by left facial paralysis, drinking choke. 1 case of local puncture taken out of bright red blood. During the hospitalization of this group of patients underwent various body examinations, 8 cases found no primary tumor; 6 cases were found to be lung cancer, liver cancer in 2 cases, thyroid cancer in 1 case.