本文报告3例用硫酸锌治疗Wilson病,经7年随访,疗效稳定。 例1 男,27岁。17岁时确诊为Wilson病。家族史阳性。用D—青霉胺治疗,效果不佳。1985年用锌剂治疗3个月,病情好转,停药后病情加重于1986年1月住院。查体:有精神症状,流涎,言语不清,进食困难,四肢粗大震颤。角膜K—F环(+)。血清铜14.01μmol/ This article reports 3 cases of Wilson’s disease treated with zinc sulfate, after 7 years of follow-up, the effect is stable. Example 1 male, 27 years old. 17-year-old diagnosed with Wilson’s disease. Positive family history. D-penicillamine treatment, the effect is not good. In 1985 with zinc treatment for 3 months, the condition improved, the condition worsened after stopping in January 1986 hospitalization. Physical examination: mental symptoms, drooling, vague words, eating difficulties, limbs tremulous. Corneal K-F ring (+). Serum copper 14.01μmol /