本文概述了希佛碱—金属络合物搞癌药剂研究的现况。在近十年中,已经合成了一系列含有N、O 或N、S 给予体的希佛碱—金属络合物,并对它们的抗癌活性进行了试验,发现其中一些化合物具有显著的抗肿瘤活性。因此,进一步研究这类化合物有着重要意义。 This article summarizes the current status of Schiff base-metal complex carcinogen research. In the last decade, a series of Schiff base-metal complexes containing N, O or N, S donors have been synthesized and tested for their anticancer activity and some of these compounds have been found to have significant resistance Tumor activity. Therefore, further study of these compounds is of great significance.