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1988年8月10日在美国国家癌症研究所进行了第一次以人工合成的 CD_4受体治疗艾滋病的临床试验。该项实验,采用美国遗传技术公司(Genentech Inc.)生产的,由哺乳动物细胞产生的该蛋白质(CD_4受体)的重组体,总共将对50个患有艾滋病或艾滋病相关综合症(ARC)的非孕期病人进行试用。ARC 病人将会有低 T-细胞计数的症状表现。旧金山综合医院也将参加该项试验。CD_4受体是化于 T_4助细胞上的艾滋病毒结合位点,艾滋病毒最初正是通过附着于这个
August 10, 1988 in the United States National Cancer Institute carried out the first synthetic CD_4 receptor in the treatment of AIDS clinical trials. In this experiment, recombinants of this protein produced by mammalian cells (CD4 receptor), produced by Genentech Inc., will evaluate a total of 50 patients with AIDS or AIDS-related complex (ARC) Of non-pregnant patients to try. ARC patients will have low T-cell count symptoms. San Francisco General Hospital will also participate in the trial. The CD4 receptor is an HIV binding site on T-4 helper cells that HIV initially attached to this