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目的以外科手术和病理分析作为参考标准,前瞻性地评估3.0T MRI比1.5T MRI对子宫颈癌术前分期的有效性。方法本研究已获得伦理委员会批准和病人书面知情同意。对31例连续的病人(年龄27～71岁,平均51.1岁)行3.0T及1.5T MR成像,完成定性及定量分析。根据局部区域分期,2位放射学专家分别独立地评估这些影像,并比较MRI所见与手术病理所见。结果 3.0T MRI的平均肿瘤信噪比、平均宫颈基质信噪比以及平均肿瘤与宫颈基质对比噪声比均显著高于1.5T MRI的(P值分别为9.1×10-6、1.8×10-6及0.008)。
Objective To evaluate the effectiveness of 3.0T MRI compared with 1.5T MRI in the preoperative staging of cervical cancer by using surgical and pathological analysis as a reference standard. Methods This study has been approved by the Ethics Committee and patients’ written informed consent. Thirty-one consecutive patients (aged 27-71 years, mean 51.1 years) underwent 3.0T and 1.5T MR imaging. Qualitative and quantitative analyzes were performed. According to the local regional staging, two radiologists independently evaluated these images separately and compared the MRI findings with the surgical pathology. Results The average tumor signal-to-noise ratio, average cervical matrix signal-to-noise ratio and mean tumor-cervical contrast ratio at 3.0T MRI were significantly higher than those at 1.5T MRI (P values were 9.1 × 10-6, 1.8 × 10-6 And 0.008).