论文部分内容阅读
The authors prospectively studied the value of clinical and neurophysiologic measurements in assessing progression in ALS.Motor unit number estimation (MUNE) and the neurophysiologic index (NI) were significantly correlated with ADM stren gth (maximal voluntary isometric contraction force in the abductor digiti minimi muscle [MVIC-ADM]). MUNE and the NI were reliable, but the NI showed a lower v ariation. On assessing progression at 3, 6, and 12 months, MUNE,NI, and MVIC-AD M showed the highest rate of change. The NI is a potentially useful new neurophy siologic measurement.
The authors prospectively studied the value of clinical and neurophysiologic measurements in assessing progression in ALS. Motor unit number estimation (MUNE) and the neurophysiologic index (NI) were significantly correlated with ADM stren gth (maximal voluntary isometric contraction force in the abductor digiti minimi muscle [MVIC-ADM]). MUNE and the NI were reliable, but the NI showed a lower voyage. On assessing progression at 3, 6, and 12 months, MUNE, NI, and MVIC-AD M showed the highest rate of change The NI is a potentially useful new neurophy siologic measurement.