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目的分析小榄地区妊娠早期妇女弓形虫(Tox)、风疹病毒(Rv)、巨细胞病毒(CMV)、单纯疱疹病毒(HSV)感染情况,为地区防治TORCH提供依据。方法对9 896例妊娠早期妇女采用罗氏E601全自动电化学发光法测定弓形体抗体(Tox-IgG和Tox-IgM)、风疹病毒抗体(Rv-IgG和Rv-IgM)、巨细胞病毒抗体(CMV-IgG和CMV-IgM);采用酶联免疫技术(捕获法)测定单纯疱疹病毒抗体(HSV-IgM)。对不同年龄组的妊娠早期妇女TORCH感染情况进行分析。结果 9 896例妊娠早期妇女Tox-IgG阳性率为17.70%,Tox-IgM阳性率为0.86%,Rv-IgG阳性率为87.79%,RvIgM阳性率为0.69%,CMV-IgG阳性率为99.22%,CMV-IgM阳性率为0.93%,HSV-IgM阳性率为0.01%;TORCHIgG在不同的年龄组差异有统计学意义(P=0.000),TORCH-IgM在不同的年龄组差异无统计学意义(P>0.05)。结论小榄地区妊娠早期妇女存在一定比例的TORCH阳性率,而Rv-IgG和CMV-IgG阳性率最高,建议本地区把TORCH免疫学检查作为产前筛查的重要指标,产前筛查TORCH阳性结果建议进行定期复查。
Objective To analyze the prevalence of Tox, Rubella (Rv), Cytomegalovirus (CMV) and Herpes Simplex Virus (HSV) infection among women in early pregnancy in Xiaolan area. Methods Ninety-nine women with early pregnancy were tested for the levels of Tox-IgG and Tox-IgM, Rv-IgG and Rv-IgM, cytomegalovirus antibody (CMV) by Roche E601 automated electrochemiluminescence -IgG and CMV-IgM); herpes simplex virus (HSV-IgM) antibody was detected by enzyme-linked immunosorbent assay (capture method). TORCH infection in women of different ages in early pregnancy was analyzed. Results The positive rate of Tox-IgM in pregnant women was 17.70%, the positive rate of Tox-IgM was 0.86%, the positive rate of Rv-IgG was 87.79%, the positive rate of RvIgM was 0.69% and the positive rate of CMV-IgG was 99.22% The positive rate of CMV-IgM was 0.93% and the positive rate of HSV-IgM was 0.01%. There was significant difference in TORCHIgG between different age groups (P = 0.000). There was no significant difference of TORCH-IgM in different age groups > 0.05). Conclusion There is a certain proportion of TORCH positive rate and the highest positive rate of Rv-IgG and CMV-IgG in women of early pregnancy in Xiaolan area. It is suggested that TORCH immunological examination should be used as an important index of prenatal screening in this area. Prenatal screening TORCH positive The results suggest regular review.