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目的 通过对糖尿病酮症中毒 (DKA)合并多器官功能衰竭 (MOF)的诱因和临床表现等进行分析 ,以提高DKA合并MOF的认识 ,及时防治。方法 采用病例回顾分析的方法 ,对我院 1997～ 2 0 0 0年 4年间收治的 5 3 7例糖尿病患者的临床资料进行总结 ,特别分析 182例DKA及其中的DKA合并MOF的患者。DKA合并MOF的诱因、临床表现、MOF的器官受累情况及转归进行总结分析。结果 分析表明DKA合并MOF的主要诱因为感染 (占 84 5 % ) ,高龄患者 (大于 60岁 )易发生MOF。MOF的主要受累器官依次为肾脏、心脏和脑等 ,MOF受累的器官数目与死亡率密切相关。结论 防治感染是减少DKA合并MOF的可能途径 ,DKA患者密切注意肾、心和脑等器官的损害 ,以防MOF。
Objective To investigate the causes and clinical manifestation of diabetic ketosis (DKA) complicated with multiple organ failure (MOF) in order to improve the understanding of DKA combined with MOF and to prevent and treat it in time. Methods The clinical data of 537 diabetic patients treated in our hospital from 1997 to 2000 were retrospectively analyzed by retrospective analysis. In particular, 182 patients with DKA and those with DKA and MOF were analyzed. The causes of DKA combined with MOF, clinical manifestations, organ involvement and outcome of MOF were analyzed. Analysis of the results showed that the main cause of DKA combined with MOF was infection (84.5%), and MOF occurred in elderly patients (older than 60 years). The main affected organs of MOF were kidney, heart and brain. The number of organs involved in MOF was closely related to mortality. Conclusion Prevention of infection is a possible way to reduce the combined use of DKA and MOF. DKA patients pay close attention to the damage of kidney, heart and brain and other organs to prevent MOF.