脓毒症是严重创伤、烧伤及休克、伴随细菌、真菌、病毒及寄生虫感染等临床极危重症患者的严重并发症之一,也是诱发脓毒性休克、多器官功能障碍综合征(multiple organizations dysfunction syndrome,MODS)的重要原因。由于脓毒症来势凶猛,病情进展迅速,病死率高,给临床救治工作带来极大困难。据统计,美国每年约有将近75万脓毒症患者,其病死率高达30%,尽管广泛采用大量临床干预措施, Sepsis is one of the serious complications of severe trauma, burns and shock, along with clinical critically ill patients such as bacteria, fungi, viruses and parasitic infections. It also induces septic shock, multiple organ dysfunction syndrome (multiple organ dysfunction syndrome) syndrome, MODS) of the important reasons. Due to the ferocious sepsis, rapid progression, high mortality, clinical treatment has brought great difficulties. According to statistics, in the United States, there are about 750,000 sepsis patients each year, and its case fatality rate is as high as 30%. Although a large number of clinical interventions are widely used,