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目的:通过分析多通道腔内阻抗-pH监测(MII-pH)阳性的胃食管反流病(GERD)患者的各项反流指标,探讨我国GERD患者的胃食管反流特点,以及性别、年龄、体位和体质指数(BMI)对反流的影响。创新点:入组患者均经MII-pH监测证实具有客观存在的胃食管反流,分析体位和BMI对反流的影响,并且发现我国GERD患者普遍存在弱酸反流。方法:有典型反流症状的疑诊GERD患者,进行24 h MII-pH监测,对监测结果阳性的患者纳入研究对象,分析其各反流指标以及性别、年龄、体位和BMI对反流的影响。结论:我国GERD患者普遍存在弱酸反流,男性、直立体位、肥胖(BMI≥25)可促进胃食管反流的发生,且年龄不是胃食管反流的危险因素。
OBJECTIVE: To investigate the gastroesophageal reflux characteristics of GERD patients in our country by analyzing the multi-channel intraluminal impedance-pH monitoring (MII-pH) -positive gastroesophageal reflux disease (GERD) , Body position and body mass index (BMI) on the impact of reflux. Innovative point: All patients were confirmed by MII-pH monitoring with an objective gastroesophageal reflux, postural and BMI analysis of the impact of reflux, and found that our common GERD patients with weak acid reflux. Methods: Patients with suspected GERD with typical reflux symptoms were monitored for MII-pH at 24 h. Patients with positive results were enrolled in the study, and their effects on reflux were analyzed, including gender, age, body position and BMI . Conclusion: Weak acid reflux is common in GERD patients in our country. Male, upright position and obesity (BMI≥25) can promote the occurrence of gastroesophageal reflux, and age is not a risk factor of gastroesophageal reflux.