714例各种癌前期病变经3月—10年的临床和内镜活检随访,发现癌变18例(2.5％),病变加重57例(8.0％),无变化354例(49.6％),好转170例(23.8％),治愈115例(16.1％)。其中病变加重及癌变率以慢性萎缩性胃炎和肠化生伴不典型增生组最高。对18例癌变病例分析表明,单凭临床表现不能识别癌变前后的特异性,对可疑癌变者应在短期内进行内镜活检随访。 714 cases of various precancerous lesions were followed up by clinical and endoscopic biopsy 3 months to 10 years. 18 cases (2.5%) were found to be cancerous, 57 cases (8.0%) were worsened, and 354 (49.6%) did not change, improving 170 In the case (23.8%), 115 cases (16.1%) were cured. Among them, aggravated lesions and cancerous rates were highest in chronic atrophic gastritis and intestinal metaplasia with atypical hyperplasia. The analysis of 18 cases of cancerous changes shows that the specificity before and after canceration cannot be identified based on clinical manifestations alone, and endoscopic biopsy follow-up should be performed for suspicious cancerous changes.