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目的探讨山东省青岛地区缺血性脑卒中危险因素的暴露情况和特点,为制定干预对策提供科学依据并指导临床预防工作的开展。方法采用回顾性病例对照研究,随机抽取2007年9月-2009年9月在青岛市市立医院首次住院的确诊为缺血性脑卒中患者(40～70岁)265例为病例组,同时间段在健康体检中心查体的健康人群(40～70岁)265人为对照组;调查并记录高血压、糖尿病、心脏病、高脂血症、高尿酸血症、超重、吸烟和饮酒8项研究指标;应用SPSS 13.0统计软件对数据进行统计学分析。结果病例组的8项危险因素暴露率均明显高于对照组(分别OR=1.428,7.422,5.055,4.886,3.139,1.487,3.274和1.800,均P<0.05);前者的总胆固醇、甘油三酯和血尿酸检测结果亦明显高于后者(P<0.01);病例组吸烟者吸烟程度较对照组严重(P<0.01)。结论青岛地区缺血性脑卒中发病危险因素在自然人群中暴露率较高。
Objective To explore the risk factors and their characteristics of ischemic stroke in Qingdao, Shandong Province, and to provide a scientific basis for the formulation of intervention measures and to guide the development of clinical prevention. Methods A retrospective case-control study was conducted. A total of 265 patients with ischemic stroke (40-70 years old) who were hospitalized for the first time in Qingdao Municipal Hospital from September 2007 to September 2009 were selected as the case group. At the same time period A total of 265 healthy people (40-70 years old) screened at the health check-up center were selected as the control group. Eight indicators of hypertension, diabetes, heart disease, hyperlipidemia, hyperuricemia, overweight, smoking and drinking were surveyed and recorded ; Statistical analysis of the data using SPSS 13.0 statistical software. Results The exposure rates of 8 risk factors in the case group were significantly higher than those in the control group (OR = 1.428, 7.422, 5.055, 4.886, 3.139, 1.487, 3.274 and 1.800 respectively, all P <0.05). The total cholesterol, triglyceride And serum uric acid test results were significantly higher than the latter (P <0.01); smokers smokers than in the control group serious smoking (P <0.01). Conclusion The risk factors of ischemic stroke in Qingdao are higher in the natural population.