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目的:探讨常规体外受精(IVF)正常形态精子百分率是否会影响获单卵患者的临床结局。方法:选择2013年1月至2015年1月在本院生殖中心接受常规IVF治疗且获卵数为1的256对夫妇,根据正常形态精子百分率的不同分为两组,其中正常形态精子百分率<4%组134例,正常形态精子百分率≥4%组122例,比较两组间的无可移植胚胎周期发生率、受精率、卵裂率、正常受精率、异常受精率、优胚率及可用胚胎率。其中新鲜移植周期共75例,正常形态精子百分率<4%组43例,正常形态精子百分率≥4%组32例,比较两组间的种植率、临床妊娠率及流产率。结果:正常形态精子百分率<4%组和正常形态精子百分率≥4%组的无可移植胚胎周期发生率、受精率、卵裂率、正常受精率、异常受精率、优胚率及可用胚胎率差异无统计学意义(P>0.05)。新鲜移植周期中,正常形态精子百分率<4%组和正常形态精子百分率≥4%组的种植率、临床妊娠率及流产率差异也无统计学意义(P>0.05)。结论:正常形态精子百分率不影响单卵患者常规体外受精的临床结局。
Objective: To investigate whether the percentage of sperm normal in vitro fertilization (IVF) affects the clinical outcome of patients with single egg. Methods: Two hundred and sixty-six couples with IVF who received IVF at our reproductive center from January 2013 to January 2015 were divided into two groups according to the percentage of normal spermatozoa. The percentage of normal spermatozoa < 134 cases in 4% group and 122 cases in normal morphology with sperm percentage≥4%. The incidence of non-transplanted embryo cycle, fertilization rate, cleavage rate, normal fertilization rate, abnormal fertilization rate, excellent embryo rate and available Rate of embryo. Among them, there were 75 fresh cycles, 43 normal sperm <4% and 32 normal sperm> 4%. The implantation rate, clinical pregnancy rate and abortion rate were compared between the two groups. Results: The non-transplanted embryo cycle rate, fertilization rate, cleavage rate, normal fertilization rate, abnormal fertilization rate, excellent embryo rate and available embryo rate of normal morphology sperm percentage <4% and normal morphology sperm percentage> 4% The difference was not statistically significant (P> 0.05). There was no significant difference in implantation rate, clinical pregnancy rate and miscarriage rate between normal morphological sperm <4% group and normal morphology sperm> 4% in fresh transplantation cycle (P> 0.05). Conclusion: The percentage of normal spermatozoa does not affect the clinical outcome of routine in vitro fertilization.