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目的研究分析综合干预对肿瘤患者Ⅳ度骨髓抑制期医院感染的预防作用,以降低医院感染率。方法选取2011年1月-2013年4月在医院进行治疗的84例肿瘤Ⅳ度骨髓抑制期患者为研究对象,将其随机分为对照组(常规干预组)42例和观察组(综合干预组)42例,对两组患者不同骨髓抑制时间及各部位感染率进行比较,数据采用SPSS14.0软件进行统计处理。结果总感染率观察组为4.76%,明显低于对照组的23.81%,且其中不同抑制时间及各部位感染率也均低于对照组,差异有统计学意义(P<0.05)。结论综合干预可有效预防控制肿瘤Ⅳ度骨髓抑制期患者的医院感染率,对于该类患者的临床应用价值较高。
Objective To study and analyze the preventive effect of comprehensive intervention on nosocomial infection in patients with grade Ⅳ myelosuppression in order to reduce the nosocomial infection rate. Methods Eighty-four patients with stage Ⅳ myelosuppression who were treated in the hospital from January 2011 to April 2013 were selected and randomly divided into control group (n = 42) and observation group (n = ) 42 cases, the two groups of different bone marrow suppression time and infection rate of each part were compared, the data using SPSS14.0 software for statistical analysis. Results The total infection rate in the observation group was 4.76%, which was significantly lower than that in the control group (23.81%). The inhibition time and the infection rate in each part were also lower than those in the control group (P <0.05). Conclusion The comprehensive intervention can effectively prevent and control nosocomial infection in patients with grade Ⅳ myelosuppression, which is of great value in clinical application.