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选择原发性肝癌患者３０例，并以健康成人３０例为对照组，对红细胞内脂质过氧化物（ＬＰＯ）含量及谷胱甘肽过氧化酶（ＧＳＨ－Ｐｘ）活性进行测定。结果显示，原发性肝癌患者红细胞ＬＰＯ含量明显高于正常对照组，Ｐ＜０．００１；红细胞ＧＳＨ－Ｐｘ活性明显低于正常对照组，Ｐ＜０．００１。提示原发性肝癌患者体内脂质过氧化作用增强，抗氧化能力低下，自由基、ＬＰＯ参与了原发性肝癌的发生及扩散。
Thirty patients with primary liver cancer were selected and 30 healthy adults were used as control groups to determine the content of lipid peroxide (LPO) and glutathione peroxidase (GSH-Px) activity in red blood cells. The results showed that the content of red blood cell LPO in patients with primary liver cancer was significantly higher than the normal control group, P <0.001; the activity of red blood cell GSH-Px was significantly lower than the normal control group, P <0.001. It is suggested that the lipid peroxidation in patients with primary liver cancer is enhanced and the antioxidant capacity is low. Free radicals and LPO are involved in the occurrence and spread of primary liver cancer.