论文部分内容阅读
用放射免疫法测定了19例慢性萎缩性胃炎(CAG)伴肠化、20例慢性萎缩性胃炎不伴肠化患者胃液CEA(癌胚抗原)、β_2mG(β_2微球蛋白)含量,以慢性浅表性胃炎作对照,结果表明:CAG伴肠化组胃液CEA浓度较CAG不伴肠化组和对照组明显升高(分别为P<0.05和P<0.01),胃液β_2mG浓度在CAG伴肠化组也较对照组明显升高(P<0.05).提示胃液CEA、β_2mG与肠化等癌前病变可能有一定关系,测定胃液CEA、β_2mG浓度对癌前病变的诊断和随访可能有一定意义.
The contents of CEA (carcinoembryonic antigen) and β_2mG (β 2 microglobulin) in gastric juice in 19 patients with chronic atrophic gastritis (CAG) with intestinal metastases and 20 patients with chronic atrophic gastritis without intestinal metastases were measured by radioimmunoassay. Epigastric inflammation was used as a control. The results showed that the concentration of CEA in gastric juice of CAG with intestinal metastasis group was significantly higher than that of CAG without intestinal metastasis group and control group (P<0.05 and P<0.01, respectively). The concentration of β_2mG in gastric juice was associated with intestinal metastasis in CAG. The group was also significantly higher than the control group (P<0.05). It may be suggested that CEA, β_2mG in gastric juice may have a certain relationship with precancerous lesions. The determination of CEA and β 2mG concentrations in gastric juice may have significance in the diagnosis and follow-up of precancerous lesions.