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目的探讨银杏达莫注射液治疗急性脑梗死的疗效及远期效果。方法选取2009年1月—2013年1月宁武县人民医院收治的急性脑梗死患者146例,随机分为试验组与对照组,各73例。试验组患者予以银杏达莫注射液治疗,对照组患者予以复方丹参注射液治疗。观察两组患者治疗前、治疗结束时、治疗后6、12个月的神经功能缺损评分(NIHSS)、日常生活活动能力(ADL)评分及不良反应发生情况。结果治疗前两组患者NIHSS及ADL评分比较,差异无统计学意义(P>0.05),治疗结束时、治疗后6、12个月试验组患者NIHSS低于对照组,ADL评分高于对照组,差异均有统计学意义(P<0.05),试验组患者不良反应发生率低于对照组,差异有统计学意义(P<0.05)。结论银杏达莫注射液治疗急性脑梗死的疗效显著,可改善患者神经功能及日常生活能力,且不良反应少,远期效果好。
Objective To investigate the curative effect and long-term effect of Yinxingdamo injection in the treatment of acute cerebral infarction. Methods One hundred and sixty-six patients with acute cerebral infarction admitted from January 2009 to January 2013 in Ningwu County People’s Hospital were randomly divided into experimental group and control group, with 73 cases in each group. Patients in the test group were treated with gingko Damo injection, and patients in the control group were treated with compound Salvia miltiorrhiza injection. The NIHSS, ADL score and adverse reactions at the end of treatment, 6 and 12 months after treatment were observed in both groups before and after treatment. Results There was no significant difference in NIHSS and ADL scores between the two groups before treatment (P> 0.05). At the end of treatment, the NIHSS in the experimental group at 6 and 12 months after treatment were lower than those in the control group, and the ADL score was higher than that in the control group. The difference was statistically significant (P <0.05). The incidence of adverse reactions in the experimental group was lower than that in the control group, the difference was statistically significant (P <0.05). Conclusion Ginkgo biloba injection has significant therapeutic effect on acute cerebral infarction, which can improve neurological function and daily living ability of patients with less adverse reactions and long-term effect.