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目的了解本院抗菌药物使用情况,为临床合理用药提供参考,保障医疗安全。方法对本院2012年1月至2012年12月临床病历及门诊处方进行回顾性统计、分析、总结。依据《国家基本药物临床用药指南》、《中国医师/药师临床用药指南》、《内科学》、《外科学》、药品说明书及相关疾病诊疗指南,进行统计和分析。结果按用药数量排在前三名的抗菌药物是:头孢呋辛钠(0.75 g)、头孢呋辛钠(1.5 g)、青霉素(80万)。本院住院抗菌药物使用率为62.05%,门诊抗菌药物使用率为19.34%,DDD值是76.80,限制级抗菌药物细菌送检率为43.74%,特殊级抗菌药物细菌送检率为45.84%,Ⅰ类切口预防用药比率为57.1%。抗菌药物使用不合理主要表现在:手术预防用药存在不合理、药物溶媒选择不合理、用法用量不合理、联合用药不合理、更换药品不合及级无指征用药。结论临床药学服务在合理用药方面发挥了重要作用。
Objective To understand the use of antibacterials in our hospital and provide a reference for clinical rational drug use to ensure medical safety. Methods The clinical records and outpatient prescriptions in our hospital from January 2012 to December 2012 were retrospectively analyzed, analyzed and summarized. Statistics and analysis were conducted based on the Guide to Clinical Drug Use of National Essential Medicines, Guide to Clinical Medication of Chinese Physicians / Pharmacists, Internal Medicine, Surgery, Manuals for Drugs and Related Diseases. Results The top three antimicrobial agents ranked by the number of drugs were cefuroxime sodium (0.75 g), cefuroxime sodium (1.5 g) and penicillin (800,000). The hospital usage of antibiotics was 62.05%, outpatient antibacterials utilization rate was 19.34%, DDD value was 76.80, restricted antibacterial drug delivery rate was 43.74%, special grade antibacterial drug delivery rate was 45.84%, Ⅰ Class incision prevention medication rate was 57.1%. Unreasonable use of antimicrobial drugs mainly manifested in: there is unreasonable use of surgical prophylaxis, drug solvent selection is not reasonable, the amount of use unreasonable, the combination of unreasonable, replacement drugs substandard level without indications medication. Conclusion Clinical pharmacy services play an important role in rational drug use.